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Project Description

MMRF » Michelson Center for Convergent Bioscience [USC] » Videos | Michelson Center for Convergent Bioscience [USC] » Making a Big Difference in Nanofabrication [Video] [2015-01-08]

Andrea Armani, John O’Brien, Dan Dapkus, Ellis Meng, Scott Fraser; Making a Big Difference in Nanofabrication [USC] [2015-01-08]

Making a Big Difference in Nanofabrication [USC] [2015-01-08]

Context

USC funds a new nanofabrication laboratory, to be built within the USC Michelson Center for Convergent Bioscience

Footage originally released on January 8, 2015

USC staff and researchers discuss the need to upgrade campus facilities and tools in order to keep up with advances in cutting edge research and innovation, including the new nanofabrication laboratory, which will be built inside the USC Michelson Center for Convergent Bioscience.

The center will house up to 30 flexible labs, Class 100 and 1,000 nanotechnology cleanrooms, and a suite of microscopy imaging technology. The nanofabrication laboratory will be focused on interdisciplinary research with next generation nanomaterials and contain characterization (surface, optical, electrical), lithography, imaging, and device integration resources.

The laboratory will allow academic institutions, national laboratories, and industrial partners to further enable nanoscale characterization and accelerate research. Both the John O’Brien Nanofabrication Laboratory and USC’s Electron and Optical Microscopy Characterization Laboratory (Center for Electron Microscopy and MicroAnalysis, CEMMA) will be in the new Michelson Center for Convergent Biosciences. The building’s anticipated opening dates is Spring/Summer 2018.

The John O’Brien Nanofabrication Laboratory was recently named after John O’Brien (1969-2017), the executive vice dean of the USC Viterbi School of Engineering, after his passing on March 31, 2017.

Transcript

    Participants:
  • Andrea Armani, Associate Professor Chemical Engineering & Material Science.
  • John O’Brien, Professor of Electrical Engineering & Executive Vice Dean for Engineering.
  • Dan Dapkus, Professor of Electrical Engineering, Physics & Astronomy – William M. Keck Distinguished Professor of Engineering.
  • Ellis Meng, Professor, Biomedical Engineering.
  • Scott Fraser, Professor of Biomedical Engineering, Director of Science Initiatives.

Andrea Armani: Nano by definition is the length scale of about 100 times smaller than the width of your hair, and fabrication means to build. So simply the definition of the word means building very, very tiny things.

John O’Brien: The current Keck clean room has served us really well; it was built in 1992 and it was built in a time when many of the faculty interests, the faculty users of the facility were building lasers, platonics, alpha communication systems. Since 1992, Viterbi has grown, USC has grown, our aspirations are grown, our faculty expertise have grown, our faculty interests have grown.

Dan Dapkus: We really need a new nanofabrication facility in order for us to keep current with research trends that exist. That enables a whole new generation of devices to be built.

Ellis Meng: In my world, it’s all about being able to build devices and in order to do that, we have to have the appropriate tool set to realize what we envision our imaginations. And so having that tool set to interact at this very small scale and to build tiny devices is critical for what we do.

Scott Fraser: Nanofabrication lets us build sensors that can get down to even single molecule sensitivity. By building a new class or molecular sensors, we can eavesdrop on the signals that pass between cells and that cause disease processes.

Andrea Armani: This type of exploration is only possible when you have all the different tools at your disposal.

John O’Brien: So we’re very excited about a new clean room to go in the basement of the Michelson Convergence for Biosciences Building. The vision of this particular building brings together in ways that we haven’t done before, scientists and engineers.

Andrea Armani: We will be able to attract industry and academia. Having those interactions can really help our students.

Dan Dapkus: We have to have facilities that enable us to do state of the art research.

Ellis Meng: We could go so much faster if we actually had a cutting-edge tool set.

Andrea Armani: Having the clean room kind of adds that foundation, is critically important to all research and all research innovation.

Scott Fraser: With the new nanofabrication center, there’s no limit to what we could accomplish.

Press Excerpts

USC Michelson center for convergent bioscience

(…) The USC Michelson Center will leverage the university’s network of scientists and engineers to tackle grand challenges in health and related fields. One key goal is to turn the biological sciences into a quantitative and predictive science, fast-tracking the detection and cure of diseases.

“In today’s rapidly evolving world, science and engineering go hand-in-hand. And the co-location of scientists and engineers in this building will only help accelerate discovery and technological innovation,” said Yannis C. Yortsos, Dean of the USC Viterbi School of Engineering.

Advances in the understanding of living systems spurred by the genome revolution, coupled with improvements in computing technology, have positioned humanity to make undreamed-of advances in the biological sciences in the near future. At the USC Michelson Center, scientists will collaborate to translate those advances to the real world by accelerating the invention of new life-saving biomedical devices. (…)

Michelson center for convergent bioscience to usher in a new era

USC broke ground today on the new USC Michelson Center for Convergent Bioscience — soon to be the largest building on campus and perhaps the catalyst for a biomedical research corridor in Los Angeles.

The center was made possible by a $50 million gift from philanthropist and retired orthopaedic spinal surgeon Gary K. Michelson and his wife, Alya Michelson. It will add 190,000 square feet of laboratories and offices for key researchers to the southwest quadrant of the University Park Campus. There, engineers and scientists will work together to tackle grand challenges in health and related fields — pioneering the advances that will one day lead to longer, healthier lives.

“The greatest advances in human history occur not merely when the sciences collaborate, but when they converge on a particular problem with strategy and purpose,” USC President C. L. Max Nikias told the standing-room only crowd.

(…) Michelson, whose own innovative work generated more patents as a sole author than Thomas Edison, has initiated life-changing research as an inventor, surgeon and philanthropist.

The center that bears his name lays the foundation for a new collaboration between the USC Dornsife College of Letters, Arts and Sciences and the USC Viterbi School of Engineering. Appropriately, it will be nestled between facilities for both schools — just west of the Dornsife Neuroscience Pavilion and north of the Olin Hall of Engineering.

(…) “The Michelson Center for Convergent Bioscience will allow our discoverers and inventors to unite forces under one roof as we seek to address the world’s most pressing health needs,” said [Steven] Kay, whose innovative work contributes to the understanding of the genetic basis for circadian rhythms, the body’s clock. “I am honored that my laboratory will be located in the center and excited for my team to begin collaborating so closely with engineers to devise innovative diagnostic devices and treatments for diseases we now consider incurable.”

The center will house flexible labs, a Center for Electron Microscopy and Analysis, a nanofabrication facility and a suite of microscopy imaging technology. Equipped with the latest and best tools, researchers will attempt to fast-track the detection and curing of diseases.

“USC Michelson will be a world-class center of the accelerating convergence between the biosciences and engineering,” said Yannis C. Yortsos, dean of USC Viterbi. “Its outstanding faculty will conduct cutting-edge bioscience and bio-engineering research that will lead to breakthrough innovations for advancing human health.”

The USC Michelson Center for Convergent Bioscience will house the John O’Brien Nanofabrication Laboratory - exterior rendering {Photo Credit: DPR Construction}The USC Michelson Center for Convergent Bioscience will house the John O’Brien Nanofabrication Laboratory – exterior rendering {Photo Credit: DPR Construction}

The USC Michelson Center for Convergent Bioscience building will feature 1 basement level and 4 levels above ground. It will house high-tech medical equipment, including the John O’Brien Nanofabrication Laboratory and an electron microscope. {Photo Credit: Largo Concrete}The USC Michelson Center for Convergent Bioscience building will feature 1 basement level and 4 levels above ground. It will house high-tech medical equipment, including the John O’Brien Nanofabrication Laboratory and an electron microscope. {Photo Credit: Largo Concrete}

The Nanofabrication Laboratory will be named after John O’Brien (1969-2017), pictured in the middle. He was the executive vice dean of the USC Viterbi School of Engineering, who recently passed away on March 31, 2017. {Photo Credit: USC}The Nanofabrication Laboratory will be named after John O’Brien (1969-2017), pictured in the middle. He was the executive vice dean of the USC Viterbi School of Engineering, who passed away on March 31, 2017. {Photo Credit: USC}

Quotes
Andrea Armani, Associate Professor Chemical Engineering & Material Science:

This type of exploration is only possible when you have all the different tools at your disposal.

John O’Brien, Professor of Electrical Engineering & Executive Vice Dean for Engineering:

(…) Viterbi has grown, USC has grown, our aspirations are grown, our faculty expertise have grown, our faculty interests have grown.

Dan Dapkus, Professor of Electrical Engineering, Physics & Astronomy – William M. Keck Distinguished Professor of Engineering:

We have to have facilities that enable us to do state of the art research.

Scott Fraser, Professor of Biomedical Engineering, Director of Science Initiatives:

With the new nanofabrication center, there’s no limit to what we could accomplish.

C. L. Max Nikias, USC President:

The greatest advances in human history occur not merely when the sciences collaborate, but when they converge on a particular problem with strategy and purpose.

Yannis C. Yortsos, dean of USC Viterbi:

Its outstanding faculty will conduct cutting-edge bioscience and bio-engineering research that will lead to breakthrough innovations for advancing human health.

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