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The R@h/BOINC workflow beings with IPD researchers who submit designed protein sequences in the queue for computing jobs managed by R@h servers; R@h then sends jobs out to volunteer computers. Once the work unit is processed and returned, an operation that is automatically managed by BOINC, IPD researchers download structures from the R@h servers. Designs with the lowest energy conformations that are structurally identical to the design are subsequently tested in the lab. Once the designs have been tested, a new round of improved designs are calculated and new tasks are sent to the volunteer computer to go through the same cycle.

The R@h/BOINC workflow beings with IPD researchers who submit designed protein sequences in the queue for computing jobs managed by R@h servers; R@h then sends jobs out to volunteer computers. Once the work unit is processed and returned, an operation that is automatically managed by BOINC, IPD researchers download structures from the R@h servers. Designs with the lowest energy conformations that are structurally identical to the design are subsequently tested in the lab. Once the designs have been tested, a new round of improved designs are calculated and new tasks are sent to the volunteer computer to go through the same cycle.