Liquid biopsy in HCC (Credit: Mount Sinai Health System / J.K. Gregory)

Liquid biopsy in HCC (Credit: Mount Sinai Health System / J.K. Gregory)

Liquid biopsy in HCC: Unlike circulating tumor cells, circulating cell-free DNA and RNA can originate from both tumor and non-tumoral tissue. Many studies demonstrate that it is feasible to analyze mutations, copy number alterations, and methylation changes from circulating tumor DNA. One of the main advantages of this technology is the simplicity for sample collection. (Credit: Mount Sinai Health System / J.K. Gregory)