Gross morphology and cavity formation of spinal cord tissue dissected at 8 weeks post-operation

Gross morphology and cavity formation of spinal cord tissue dissected at 8 weeks post-operation

The PLGA and PLGA-PEG nanofibers both contributed to tissue structural integrity, whereas a large gap in the lesion site was still present in the control group (A). In both of PLGA and PLGA-PEG group, cavity areas were reduced compared with control group (B). The smallest cavity area was observed in PLGA-PEG group. However, larger cavities were observed in the PLGA group (P<0.05, Student t-test, n = 3) (C). doi:10.1371/journal.pone.0117709.g014