(Figure 7A) PF Reduces IGF-1/PKA to Promote Lineage-Balanced Hematopoietic Regeneration

(Figure 7A) PF Reduces IGF-1/PKA to Promote Lineage-Balanced Hematopoietic Regeneration

PF Reduces IGF-1/PKA to Promote Lineage-Balanced Hematopoietic Regeneration

(Figure 7A) A simplified model for a partially conserved nutrient signaling PKA pathway in yeast and mammalian cells. Arrows show activating actions, and horizontal bars indicate inhibitory actions. GH, growth hormone; AC, adenylate cyclase; PKA, protein kinase A; CREB, cAMP response element binding protein; Foxo1, Forkhead box protein O1; G9a, H3 Lys-9 methyltransferase.