...Changing The World

Sabin Vaccine Institute.

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The Sabin Vaccine Institute (Sabin) is a non-profit, 501(c)(3) organization of scientists, researchers, and advocates dedicated to reducing needless human suffering from vaccine-preventable and neglected tropical diseases (NTDs). Since its founding in 1993, Sabin has been at the forefront of global efforts to prevent and eliminate infectious and neglected tropical diseases.

To achieve this mission, Sabin develops new vaccines, advocates for increased use of existing vaccines and promotes expanded access to affordable medical treatments.

The Sabin Vaccine Institute Product Development Partnership is a non-profit research and development model that works to address diseases that have no available vaccine. Working together with a network of global partners, Sabin is spearheading research and development projects that will benefit hundreds of millions of people suffering from diseases including hookworm, schistosomiasis, leishmaniasis, ascariasis, trichuriasis, Chagas disease and severe acute respiratory syndrome (SARS).

Sabin | Vaccine Development
  • Human Hookworm
  • The Sabin PDP is the only product development partnership in the world targeting human hookworm infection which would alleviate the suffering of more than half a billion infected people.
  • Schistosomiasis
  • In 2008, Sabin PDP launched an initiative to develop a vaccine against schistosomiasis, which infects over 200 million people around the world and is the deadliest disease of the seven most prevalent NTDs, killing an estimated 280,000 people annually.
  • Chagas Disease/Leishmaniases
  • The Sabin PDP recently initiated development for a new therapeutic vaccine for Chagas disease that will be undertaken with partners in Mexico, where between one and six million people are infected with this leading cause of poverty in Latin America.
  • SARS Vaccine
  • The product development processes for the prototype vaccine against SARS are being developed at the Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development. The vaccine is expected to be ready for clinical testing by 2017.
  • Soil-Transmitted Helminth (STH)
  • Sabin PDP recently launched a soil-transmitted helminth (STH) vaccine discovery program. The program will focus on eradicating two major ailments: Ascariasis, a disease of the small intestine which affects an estimated 0.8-1.3 billion and Trichuriasis, an infection of the large intestine which affects about 600 to 800 million people. Both infections are known to significantly impede both physical and cognitive growth in children.

Sabin’s Vaccine Advocacy and Education programs work with leading international experts and organizations to promote awareness of infectious diseases and the immunizations necessary to combat them. By educating leaders from national governments, the private sector, media and civil society organizations on the value of immunization and the burden of disease, and by encouraging collaboration among all development partners on vaccine issues, Sabin works to improve global awareness, access, policy and action.

The Global Network for Neglected Tropical Diseases, an advocacy initiative of the Sabin Vaccine Institute, works to raise the awareness, political will and funding necessary to control and eliminate the seven most common neglected tropical diseases. The Global Network works to raise awareness that for only 50 cents per person annually, a packet of pills can be administered to treat all seven of the most common NTDs.

Sabin’s diverse partnerships are important to achieving the organization’s mission. Sabin partners with governments, multi-lateral and bi-lateral institutions, academic institutions, scientists, medical professionals, and non-profit organizations in our work to further reduce human suffering from devastating infectious and neglected tropical diseases.

Sabin was founded on the legacy and global vision of one of medicine’s most pre-eminent scientific figures, Dr. Albert B. Sabin, who is best known for developing the oral live virus polio vaccine. Dr. Sabin not only dedicated his entire professional career to groundbreaking medical advancements to reduce human suffering, he also waged a tireless campaign against the health inequities of poverty.

Through a comprehensive approach that relies on scientific innovation, as well as the nuances of advocacy, communications and partnership cultivation, Sabin carries this mission forward.



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